The STR/ort mouse model of spontaneous osteoarthritis – an update

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The STR/ort mouse model of spontaneous osteoarthritis – an update

Osteoarthritis is a degenerative joint disease and a world-wide healthcare burden. Characterized by cartilage degradation, subchondral bone thickening and osteophyte formation, osteoarthritis inflicts much pain and suffering, for which there are currently no disease-modifying treatments available. Mouse models of osteoarthritis are proving critical in advancing our understanding of the underpin...

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ژورنال

عنوان ژورنال: Osteoarthritis and Cartilage

سال: 2017

ISSN: 1063-4584

DOI: 10.1016/j.joca.2016.12.014